Brown the ground beef in a large skillet over medium-high heat, breaking it up as it cooks. Drain off the fat.
In a medium saucepan, warm the pork and beans over medium heat. Stir in the brown sugar and ketchup — here's the move: taste it and adjust that sweet-tangy balance like you're building a cocktail. You want the brown sugar's molasses depth playing against the ketchup's acidity.
Preheat your oven to 375°F. Combine the browned beef and seasoned beans in a 2.5-quart casserole dish.
Place the biscuits on a baking sheet and par-bake for 4 minutes — just enough to set them but keep them tender inside.
Nestle the partially baked biscuits on top of the bean mixture, then scatter the torn cheese over everything. Look, this is comfort food at its finest — the biscuits will soak up just enough of that sweet bean sauce while staying fluffy on top.
Cover and bake at 350°F for 20-30 minutes, until the biscuits are golden and the filling is bubbling around the edges.
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