Preheat oven to 375°F. Season chicken breasts generously with salt and pepper, then arrange in a buttered 9x13 inch baking dish.
Combine quartered artichoke hearts, grated Parmigiano, mayonnaise, and minced garlic in a bowl. Mix thoroughly. (Don't skip the fresh garlic - garlic powder won't give you the same depth.)
Spread the artichoke mixture evenly over each chicken breast, creating a thick coating.
Bake uncovered for 30-35 minutes until chicken reaches 165°F internal temperature and the topping is golden.
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